EliseAI raises $250M in series E funding led by Andreessen Horowitz, doubling valuation to $2.2B

New York-based EliseAI has quietly turned itself into one of the most interesting players in enterprise automation. The startup just raised $250 million in a Series E round led by Andreessen Horowitz, doubling its valuation to more than $2.2 billion, the company announced Wednesday. The fresh capital follows a year in which the company crossed $100 million in annual recurring revenue and doubled its headcount.

The pitch is simple but ambitious: take industries weighed down by bureaucracy and repetitive manual tasks—healthcare and housing—and hand them over to software that actually works.

Founded in 2017 by Minna Song (CEO) and Tony Stoyanov (CTO), EliseAI has been building vertical-specific AI systems that can run call centers, manage patient scheduling, and field apartment rental requests without the endless back-and-forth that usually burns out staff and frustrates customers.

The latest funding comes from Andreessen Horowitz with participation from Bessemer Venture Partners, Sapphire Ventures, and Navitas Capital. Investors are betting that vertical AI can succeed where broad general-purpose models struggle—by automating messy, highly regulated workflows in sectors that represent nearly 40% of household spending in the U.S.

“EliseAI is built on the belief that AI can dramatically improve how critical industries operate,” said Song. “For an average American, healthcare and housing represent approximately 40% of household spending. These two systems are notoriously complex, outdated, and painful to navigate. And we’re here to fix it with agentic AI.”

The company has momentum to back up the pitch. Since raising $75 million in August 2024, EliseAI has grown from 150 to more than 300 employees and rolled out new products across its two core verticals. In healthcare, its software now handles multi-step scheduling, prior authorizations, and even nuanced patient concerns, cutting administrative overhead by up to 25%. For practices like Women’s Health CT, the platform has already changed how OB-GYN call centers operate, reducing wait times and improving staff efficiency.

On the housing side, EliseAI’s tools include AI-guided tours, lease audits, fee transparency tools, and a maintenance app. The company says it already supports 600 owners and operators, covering 10% of the U.S. apartment market and 75% of the NMHC Top 50 Operators. That kind of footprint explains why investors see more headroom, with international expansion now in the mix.

Alex Immerman, a16z Growth partner, said EliseAI is “raising the standard for how people experience two of life’s most essential services: housing and healthcare.”

EliseAI will use the fresh capital infusion to double the team again, with hiring underway across engineering, customer experience, sales, marketing, and operations. The company is growing hubs in New York, San Francisco, Boston, and Chicago, underscoring how quickly it’s scaling.

Administrative bloat is one of the most expensive problems in healthcare, costing more than $600 billion annually in the U.S. alone. If EliseAI can continue shaving down those costs and prove it can run at scale, its bet on vertical AI could end up looking prescient.

EliseAI Team (Credit: EliseAI)